Ferredoxin 6 Antibodies

Target Information

Ferredoxin 6 encodes a small soluble iron-sulfur electron-transfer protein that is typically cytosolic in bacteria and functions as a monomeric ferredoxin. Structural studies of the Rhodobacter capsulatus protein show an approximately 106-amino-acid fold dominated by a compact beta-grasp/ferredoxin-like architecture that houses a single buried 2Fe-2S prosthetic group coordinated by conserved cysteine residues; the cluster sits in a largely hydrophobic pocket close to, but not fully exposed at, the protein surface, consistent with partner-specific protein-protein electron-transfer interactions. Functionally, ferredoxin 6 belongs to a subset of bacterial 2Fe-2S ferredoxins proposed to participate in iron-sulfur cluster biogenesis/handling rather than broad photosynthetic electron distribution, and comparative/functional analyses in R. capsulatus support the presence of multiple specialized ferredoxins with nonredundant roles in cellular redox metabolism, including pathways linked to metallocluster-dependent processes.

Synonyms

Aq_1622a; Fd6; FDX6